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Evaluation of Antifasciola Efficacy of Artemisia Maritima in Relation to Closantal and Triclabendazole in Bovines Affected With Fasciolosis

Imtiyaz Ahmad Reshi Rajiv Singh A. H. Bhat S. R. Upadhyay I. A. Shah
Vol 7(5), 134-139
DOI- http://dx.doi.org/10.5455/ijlr.20170330052752

Parasitism in livestock is a cause of concern for animal health and production. Among helminth infections, fasciolosis is of paramount importance due to its wide host range. Resistance of flukes against commonly available flukicides has been reported from various parts of the world. To overcome this limitation and dependency over the limited anthelmintics, herbal preparation, Artemisia maritima was used to treat this infection. The in- vivo trial was conducted on 18 bovines (divided in 3 groups, G1, G2 and G3) naturally infected with Fasciola spp. G1 animals were treated with Artemisia maritima powder @750 mg/kg BW orally, G2 and G3 animals received a single oral dose of closantel @7.5 mg/kg BW and triclabendazole @12 mg/kg BW orally, respectively. Each group was monitored for a period of 21 days post treatment. Six infected animals were kept as infected untreated (positive) control (G-4) and same number of apparently healthy animals free from endoparasitic infestation was kept as uninfected and untreated (negative) control. Pre and post-treatment values of biochemical and mineral parameters in Fasciola infected bovine was estimated. Triclabendazole and closantel showed significant (p<0.05) increase in TPP, albumin, A: G ratio, AST, Ca and P levels 21 days after treatment whereas, Artemisia maritima treated group showed non-significant improvement.

Keywords : Fasciolosis Artremisia Closental Triclabendazole

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