NAAS Score 2019

                   5.36

Declaration Format

Please download DeclarationForm and submit along with manuscript.

UserOnline

Free counters!

Previous Next

Nitric Oxide: A Prime Signaling Molecule in Bovine Male Reproduction

R. A. Siddique Shabana N. Ali M. K. Bharti Ajit Kumar Anand Kumar T. Ambwani
Vol 9(8),11-36
DOI- http://dx.doi.org/10.5455/ijlr.20180320063007

Nitric oxide (NO•) is an important bioactive molecule with a short half-life. It is synthesized from the enzymatic conversion of L-Arg to L-citrulline in presence of nitric oxide synthases (NOS) and cofactors. The level of NO• is very important as it shows beneficial effects at lower concentration whereas cytotoxic at higher concentration. It acts as protective agent and maintains post thaw motility and viability of spematozoa. NO• plays critical importance in penile erection by relaxing the smooth muscle via inhibiting Rho A/ Rho-kinase pathway. It also participates in spermatogenesis, capacitation and acrosome reaction via cAMP/ cGMP pathways in mammals. Systemic inhibition of NOS caused impaired copulation, decreased erections and alteration in aggressive behaviour. Inhibition of cNOS significantly reduced the invitro fertilization, sperm-zona pellucida binding and proper embryonic development. Therefore, the cross talk and multiple systems induced by NO• act parallelly, safeguard the timely function of the spermatozoa responsible for fertilization.

Keywords : Aggression Capacitation and Acrosome Reaction Erectile Dysfunction Mating Behaviour Nitric Oxide Signaling Event Spermatozoa Protective Action

Full Text Read : 74 Downloads : 18
Previous Next

Submit Case Reports for Special Issue (Dec’19)

Recommend IJLR to include in UGC-CARE list

Download Completed format here

IJLR_UGC CARE Recommendation

And

Recommendations of new journals should be routed by universities and colleges as follows:

  1. Universities: IQAC cell to respective regional CARE University
  2. Affiliated colleges: College IQAC cell to parent university’s IQAC cell. Parent university IQAC cell will forward to respective regional CARE University.

You can find Zonal UGC-CARE address here https://ugccare.unipune.ac.in/site/website/ugc-contact.aspx

Close