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Quinolone Arthropathy in Broiler Chicken Administered with Enrofloxacin

Veerapandian Sureshkumar Ghadevaru Sarathchandra
Vol 9(2), 211-216
DOI- http://dx.doi.org/10.5455/ijlr.20180829052001

Arthropathic potential of enrofloxacin was investigated in broiler chicken at recommended therapeutic dose. Day old broiler chicks were randomly divided into 4 groups each comprising 6 birds. Group I, control birds received non medicated water, while group II, III, IV and V were medicated with enrofloxacin at recommended therapeutic dose 10mg/Kg body weight in drinking water for 5 successive days from 43rd to 47th day of age. Juvenile cartilages were collected on 1, 3, 5 and 9 days after the last dose from respective treatment groups and subjected to histopathological examination. Degeneration of chondrocytes was noticed in day 1 post treatment group and shrunken chondrocytes with pyknotic nuclei were observed till 5th day post treatment. However, clumping of chondrocytes observed on day 5 post treatment and a few cases of degenerated chondrocytes on day 9 post treatment around the blood vessels, suggestive of reversal in chondrocyte lesions.

Keywords : Arthropathy Broiler Chicken Enrofloxacin Juvenile Cartilages

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