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A Study on Chlorpyrifos Induced Oxidative Stress in Broiler Chickens

Henna Wani Shafiqur Rehman Shabu Shoukat Navdeep Kour Sahil Dutta
Vol 7(3), 22-33
DOI- http://dx.doi.org/10.5455/ijlr.20170215040614

The present investigation delineates role of free radicals in inducing tissue damage in the vital organs viz. the liver, kidneys and brain in chlorpyrifos toxicity in broilers. A total of 72 experimental birds were selected for present study. These experimental birds were divided into 4 groups viz. Group І (Control), Group II, III and IV, comprising of 18 broiler birds each. Chlorpyrifos in corn oil was administered orally on daily basis to each group 2Qof birds @ 3.2, 1.6 and 0.64 mg/kg respectively, for a period of 6 weeks. The liver, kidneys and brain tissues of these experimental birds were evaluated to reveal the free radical damage due to chlorpyrifos. Significant increase in Lipid peroxidation (LPO) and decrease in levels of superoxide dismutase (SOD) and catalase (CAT enzymes) in these organs indicated cell injury due to oxidative stress caused by free radicals in chlorpyrifos toxicity.

Keywords : Oxidative Stress Broiler Birds Chlorpyrifos Brain Lipid Peroxidation Superoxide Dismutase Catalase

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