Four isonitrogenous dietary treatments were evaluated for their effect on nutrient utilization of crossbred (LWY x Desi) male pigs (15.24 kg ± 0.21) during grower and finisher phases in a completely randomized design. The basal diet include corn-soybean meal based diet mixed with 100g Probiotic (Bacillus) and 500 g enzyme cocktail per ton feed. The dietary treatments constitute rice dried distillers grain solubles (DDGS) in basal ration (control; T1) at 20% (T2), 30% (T3), and 40% (T4) levels. During grower phase, the digestibility coefficients of DM and EE was higher (P<0.05) in pigs fed basal diet and the calcium and phosphorus digestibility (%) was higher (P<0.05) for DDGS included rations with highest in 40% DDGS ration. The nitrogen loss (g/d) in urine was lower (P<0.05) in T1 fed pigs. The total nitrogen loss (g/d) was higher (P<0.05) for 30% and 40% DDGS rations. The total calcium loss (g/d) was not significantly different among the treatments. Phosphorus retention (g/d) was higher (P<0.01) in DDGS diets compared to those fed on basal ration. The intake, faecal, and urinary gross energies were not significantly different among the treatments. During finisher phase, none of the nutrient digestibility of the nutrients, except phosphorus was found to be significant. The nitrogen retention (% intake) was higher (P<0.05) for basal diets. Phosphorus retained (g/d) was higher (P<0.05) for DDGS diets. None of the energy balance parameters was significant. It was concluded that DDGS could replace 30% of protein in the swine diets without any deleterious effects on the nutrient digestibility.