Therapeutic management of Babesia canis induced cerebra babesiosis in a German shepherd dog

Authors

  • Deepika Singh
  • Rajat Singh
  • Deshdeepak
  • M V Jithin
  • Ajit Kumar Singh
  • Arbind Singh
  • V K Varun
  • Amit Verma a:1:{s:5:"en_US";s:14:"SVPUAT, Meerut";}

Keywords:

Cerebral babesiosis, doxycycline, Imidocarb, tetraparesis, ticks

Abstract

A four years old male German shepherd dog was presented to Veterinary Clinical Complex, SVPUAT, Meerut, Uttar Pradesh with a history of scrotal infection, pyrexia, tetraparesis, generalized seizures, blindness, stupor and vocalization. Clinical examination revealed lymphadenopathy, loss of pupillary reflex, tetraparesis, elevated rectal temperature (1050F), tachyarrhythmia and infestation of Rhiphicephalus spp ticks. On the basis of clinical signs, the case was tentatively diagnosed as cerebral babesiosis and the patient was transferred to the critical care unit. Blood sample was collected for blood smear and hematobiochemical examination. The therapy was initiated with topical bath of water, oxygen therapy and rectal administration of diazepam, intravenous administration of fluid therapy, Mannitol, doxycycline, flunixin meglumyne and B complex for 5 days. Imidocarb dipropionate was subcutaneously administered @ 6.6 mg/kg body weight. Improvement in condition of dog was appreciated with establishment of normal rectal temperature, absence of seizure for next twenty four hours and improvement in the demeanour of dog. Drugs were well tolerated by the dog with establishment of appetite from day 5 and complete recovery after 21 days

References

Gonde, S., Chhabra, S., Uppal, S. K., Singla, L. D. & Randhawa, S. S. (2016). A unique case of Babesia gibsoni infected dog with paraplegia. Journal of Parasitic Diseases, 40, 1605-1608.

Irwin, P. J. (2010). Canine babesiosis. Veterinary Clinics: Small Animal Practice, 40(6), 1141-1156.

Keller, N., Jacobson, L. S., Nel, M., de Clerq, M., Thompson, P. N., & Schoeman, J. P. (2004). Prevalence and risk factors of hypoglycemia in virulent canine babesiosis. Journal of Veterinary Internal Medicine, 18(3), 265-270.

Jacobson, Linda S. & Clark, I. (1994). The pathophysiology of canine babesiosis: new approaches to an old puzzle. Journal of the South African Veterinary Association, 65(3), 134-145.

Adaszek, Ł., Łyp, P., & Winiarczyk, S. (2017). Canine babesiosis–in the light of own study. BIG PROBLEM, Veterinary Magazine for companion animal practitioner, 2, 9. (ISSN 2544-0950)

Schetters, T. P., & Eling, W. M. C. (1999). Can Babesia infections be used as a model for cerebral malaria? Parasitology today, 15(12), 492-497.

Chao, L. L., Liao, H. T., Ho, T. Y., & Shih, C. M. (2017). First detection and molecular identification of Babesia gibsoni from Rhipicephalus sanguineus ticks. Acta tropica, 166, 356-362.

Van de Maele, I., Savary-Bataille, K., Gielen, I., & Daminet, S. (2008). An unusual form of canine babesiosis. The Canadian Veterinary Journal, 49(3), 283.

Boozer, A. L., & Macintire, D. K. (2003). Canine babesiosis. Veterinary Clinics: Small Animal Practice, 33(4), 885-904.

Sikorski, L. E., Birkenheuer, A. J., Holowaychuk, M. K., McCleary‐Wheeler, A. L., Davis, J. M., & Littman, M. P. (2010). Babesiosis caused by a large Babesia species in 7 immunocompromised dogs. Journal of veterinary internal medicine, 24(1), 127-131.

Lin, M. Y., & Huang, H. P. (2010). Use of a doxycycline-enrofloxacin-metronidazole combination with/without diminazene diaceturate to treat naturally occurring canine babesiosis caused by Babesia gibsoni. Acta Veterinaria Scandinavica, 52(1), 1-4.

Matsuu, A., Koshida, Y., Kawahara, M., Inoue, K., Ikadai, H., Hikasa, Y. & Higuchi, S. (2004). Efficacy of atovaquone against Babesia gibsoni in vivo and in vitro. Veterinary parasitology, 124(1-2), 9-18.

Jacobson, L. S. (2006). The South African form of severe and complicated canine babesiosis: clinical advances 1994–2004. Veterinary parasitology, 138(1-2), 126-139.

Solano-Gallego, L., & Baneth, G. (2011). Babesiosis in dogs and cats—expanding parasitological and clinical spectra. Veterinary parasitology, 181(1), 48-60.

Bohm, M., & Leisewitz, A. L. (2006). Capillary and venous Babesia canis parasitaemias and their association with outcome of infection and circulatory compromise. Veterinary Parasitology, 141, 18-29.

Solano-Gallego, L., Sainz, A., Roura, X., Estrada-Pena, A., & Miro, G. (2016). A review of canine babesiosis: the European perspective. Parasites & vectors, 9, 1-18.

Schetters, T. P. M., Moubri, K., & Cooke, B. M. (2009). Comparison of Babesia rossi and Babesia canis isolates with emphasis on effects of vaccination with soluble parasite antigens: a review. Journal of the South African Veterinary Association, 80(2), 75-78.

Vercammen, F., De Deken, R., & Maes, L. (1996). Prophylactic treatment of experimental canine babesiosis (Babesia canis) with doxycycline. Veterinary parasitology, 66(3-4), 251-255.

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Published

18-05-2024

How to Cite

Singh, D., Singh, R., Deshdeepak, Jithin, M. V., Singh, A. K., Singh, A., … Verma, A. (2024). Therapeutic management of Babesia canis induced cerebra babesiosis in a German shepherd dog. International Journal of Livestock Research, 14(4). Retrieved from http://ijlr.org/ojs_journal/index.php/ijlr/article/view/303

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