Therapeutic Efficacy of Curcumin and Artemisia absinthium against Coccidiosis in Goat

M. M. Raut; M. F. M. F. Siddiqui; M. P. Sakhare; T. A. Shafi; P. V. Yeotikar; G. M. Chigure; S. Sajid Ali; S. D. Chepte; S. R. Shaikh

Authors

M. M. Raut PG Scholar, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, MAFSU, Parbhani (MS) – 431 402 INDIA
M. F. M. F. Siddiqui I/C Professor and Head, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, MAFSU, Parbhani (MS) – 431 402 INDIA
M. P. Sakhare Associate Professor, Department of Veterinary Epidemiology and Preventive Medicine, College of Veterinary and Animal Sciences, MAFSU, Parbhani (MS) – 431 402 INDIA
T. A. Shafi Assistant Professor, Department of Veterinary Epidemiology and Preventive Medicine, College of Veterinary and Animal Sciences, MAFSU, Parbhani (MS) – 431 402 INDIA
P. V. Yeotikar Professor and Head, Department of Veterinary Biochemistry, College of Veterinary and Animal Sciences, MAFSU, Parbhani (MS) – 431 402 INDIA
G. M. Chigure Associate Professor, Department of Veterinary Parasitology, College of Veterinary and Animal Sciences, MAFSU, Parbhani (MS) – 431 402 INDIA https://orcid.org/0000-0002-6067-0423
S. Sajid Ali Associate Professor, Department of Animal Genetics and Breeding, College of Veterinary and Animal Sciences, MAFSU, Parbhani (MS) – 431 402 INDIA https://orcid.org/0000-0003-1226-0910
S. D. Chepte I/C Professor and Head, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, MAFSU, Parbhani (MS) – 431 402 INDIA
S. R. Shaikh PhD Scholar, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, MAFSU, Parbhani (MS) – 431402 INDIA https://orcid.org/0000-0002-3536-1194

Keywords:

Goat, Coccidia, Curcumin, Artemisia absinthium, OPG, Herba

Abstract

The present research study was conducted to determine the anti-coccidial activity of Curcumin and Artemisia absinthium in coccidiosis-infected goats. In this study kids age group, 0-3 months having clinical signs such as diarrhoea, pale mucus membrane and Oocyst Per Gram > 200 was randomly divided into three groups, 10 animals each, Group I treated with Curcumin @ 4.3 mg per kg body weight orally for 14 days, Group II treated with ethanolic extract of A. absinthium @ 2 gm per kg body weight orally single dose and Group III treated with Amprolium @ 55 mg per kg body weight orally for 19 days. To check the efficacy of treatment faecal and blood sample was collected on the 7th, 14th, and 21st day after the treatment. There was a significant improvement in the clinical parameters, viz. temperature, heart rate, and respiration rate, in all treatment groups after treatments. The values of Hb, VPRC, and TEC total protein, albumin, and globulin were increased significantly improved after treatments in all groups. There was a decrease in Oocyst count in-group I treated with Curcumin, the maximum decrease in OPG count was 79.75 %. Group II showed the maximum decrease in OPG count was 74.5 %, and group III showed a maximum decrease in OPG count was 95.49 %. In conclusion, Curcumin and A. absinthium have potential anti-coccidial activity by significant reduction of oocysts and clinical improvements against coccidiosis in goat.