A Comparative Study on Ultrasonographic and Bio-Chemical Changes with Histopthological Changes of Uterus in Pyometra Affected Bitches

Abstract

The aim of the study was to compare the bio-chemical and histopathological changes with the ultrasonographic findings of uterine wall thickness in bitches affected with pyometra. The study was conducted in 30 experimental and 10 control bitches. There was a significant (P<0.05) elevation in the serum BUN, creatinine, globulin and total protein levels in pyometra affected bitches. During ultrasonongphic examination the uterine wall thickness was measured using electronic calipers. In normal bitches the uterine wall thickness was 2.56 mm whereas the thickness increased from 8.92 mm to 18.23 mm in the affected bitches. The biochemical profiles were correspondingly higher as the uterine wall thickness increased. The loss of endometrial surface, enlargement of endometrial glands and bursting of glands were noticed during histopathological examination as the wall thickness increased.