SNP1 (G-1539A) of Toll- Like Receptor 4 Gene Polymorphism in Indigenous Cattle of North East India vis-a-vis Crossbred Cattle

Authors

  • Chukham Gohain Department of Animal Genetics and Breeding https://orcid.org/0000-0002-9742-6635
  • Keyolenu Yore Department of Animal Genetics and Breeding, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl, Mizoram, INDIA
  • Lalhruaitluangi Department of Animal Genetics and Breeding, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl, Mizoram, INDIA
  • G. Poulinlu Department of Veterinary Microbiology, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl, Mizoram, INDIA
  • P. Mayengbam Department of Veterinary Physiology and Biochemistry, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl, Mizoram, INDIA
  • N. Shyamsana Singh Department of Animal Genetics and Breeding, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl, Mizoram, INDIA
  • T.C. Tolenkhomba Department of Animal Genetics and Breeding, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl, Mizoram, INDIA

Keywords:

Indigenous Cattle, Gene Frequency, North East India, Toll- like Receptor 4 Gene

Abstract

The study was conducted to study the polymorphism in bovine Toll-like Receptor 4 gene in 160 indigenous cattle of North East India (viz. Manipur, Mizoram and Assam) and crossbred cattle. Two different variants of SNP1 (G-1539A) of TLR4 gene viz. A and G were detected by PCR-RFLP using BglI. The frequency of A allele was predominant (0.513) among Manipur indigenous cattle. On the contrary, the frequency of G allele was predominant in indigenous cattle of Mizoram and Assam and crossbred cattle. Among the genotypes, GG genotype was found in moderate to intermediate frequency among the local cattle of North East India. While the genotype GG was high in the crossbred population. The population conforming to equilibrium indicated lack of selection pressure in these cattle population.

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Published

31-12-2018

How to Cite

Gohain, C., Yore, K., Lalhruaitluangi, Poulinlu, G., Mayengbam, P., Singh, N. S., & Tolenkhomba, T. (2018). SNP1 (G-1539A) of Toll- Like Receptor 4 Gene Polymorphism in Indigenous Cattle of North East India vis-a-vis Crossbred Cattle. International Journal of Livestock Research, 8(12), 58–63. Retrieved from https://ijlr.org/ojs_journal/index.php/ijlr/article/view/1443

Issue

Vol. 8 No. 12 (2018): International Journal of Livestock Research

Section

Articles

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