Surgico-Chemotherapeutic Management of Splenic Hemangiosarcoma Using VAC Protocol in German Shepherd Dog- a Case Report
DOI:
https://doi.org/10.5455/ijlr.20210217045123%20%20%20%20%20Keywords:
Echo Dense, Incoordination, Neurological, Seizure, SplenomegalyAbstract
A 9yr uncastrated German Shepherd dog was presented to the Teaching Veterinary Clinical Complex with a history of Anorexia, weakness, weight loss, Lameness, intermittent sudden collapse and muscular incoordination. On further investigation it was found that dog was earlier having a history of seizures of unknown etiology. Initially the case was misdiagnosed as certain neurological conditions and the treatment led deterioration of the condition. Thus, whole body check-up was recommended the very next time. Thoracic radiograph revealed no abnormal findings while Abdominal Radiograph confirmed certain degree of splenomegaly. Ultrasonographic findings confirmed a highly echo dense structure at the cranial pole of spleen concluding it to be a splenic mass of about 4.93 cm. Animal was kept on vincristine doxorubicin and cyclophosphamide therapy (VAC Protocol) and continuous fluid maintenance therapy. Splenectomy was performed under General Anaesthesia through hilar ligation technique.
References
Brown,N.O., Patnaik, A.K. and MacEwen E.G. (1985).Canine hemangiosarcoma: Retrospective analysis of 104 cases. Journal of American Veterinary Medical Association, 186: 56-58.
DeHoff, W.D. and Greene, R.W. (1973). Gastric Dilatation and the gastric torsion complex. Veterinary clinics of North America. Small Animal Practice, 2: 141-153.
deMadron, E., Helfand, S.C. and Stebbins, K.E. (1987). Use of chemotherapy for treatment of cardiac hemangiosarcoma in a dog. Journal of American Veterinary Medical Association,190:887-891.
Hammer, A.S., Couto, C.G., Swardson, C. and Getzy, D. (1991). Haemostatic abnormalities in dogs with hemangiosarcoma. Journal of Veterinary Internal Medicine,5(1):11-14.
Johnson, K.A., Powers, B.E., Withrow, S.J., Sheetz, M.J., Curtis, C.R. and Wrigley, R.H. (1989). Splenomegaly in dogs. Predictors of neoplasia and survival after splenectomy. Journal of Veterinary Internal Medicine, 3(3):160-166.
Oksanen, A. (1978). Haemangiosarcoma in dogs. Journal of Comparative Pathology, 88:922-6.
Prymak, C., McKee, L.J., Goldschmidt, M.H. and Glickman, L.T. (1988). Epidemiologic, clinical, pathologic, and prognostic characteristics of splenic hemangiosarcoma and splenic hematoma in dogs: 217 cases (1985). Journal of American Veterinary Medical Association, 193(6):706-712.
Pulley, L.T. and Stannard, A.A. (1990). Tumors of the skin and soft tissue. In: Moulton JE, ed. Tumors in domestic animals. 3rd ed. Berkeley, CA: University of California Press,47–8.
Rosenberg, S.A. (1985). Adjuvant chemotherapy of adult patients with soft tissue sarcomas. In: DeVita VT, Hellman S, Rosenberg SA, eds: lmportant Advances in Oncology. Philadelphia, PA: JB Lippincott.
Sartor, A.J., Bentley, A.M. and Brown, D.C. (2013). Association between previous splenectomy and gastric dilatation volvulus in dogs: 453 cases (2004-2009). Journal of American Veterinary Medical Association, 242(10):1381-1384.
Spangler, W.L. and Culbertson, M.R. (1992). Prevalance, type, and importance of splenic diseases in dogs: 1480 cases (1985-1989). Journal of American Veterinary Medical Association, 200: 829-834.
Van Vechten, M., Helfand, S.C. and Jeglum, K.A. (1990). Treatment of relapsed canine lymphoma with doxorubicin and dacarbazine. Journal of Veterinary internal Medicine, 4:187-191.
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