The present study aimed to generate baseline data on physiological and haemato-biochemical profile of local chicken, Sikhar of Mizoram. Body weight, respiration rate (RR), pulse rate (PR) and rectal temperature (RT) were recorded. Hb, TEC, PCV, MCV, MCH, MCHC, blood glucose, total protein (TP), albumin, globulin and total cholesterol (TCh) were estimated in plasma samples collected from five groups viz. 2 months, 4 months, 6 months, 8 months and 10 months old. Sikhar birds attained 217.92±7.11g of body weight at 2 months and 1134.20±69.58 g at 10 months. RR and PR declined gradually with age while RT was highest in 4 months old birds. Sikhar birds maintained stable glucose level till 8 month and declined at 10 months. Hb, TEC, TP, albumin and globulin increased while MCV and MCH declined with age. PCV and MCHC were not influenced by age. TCh fluctuated in different groups with highest value at 4 months.