Current Trends in SNP Analysis with Special Reference to Candidate Genes Associated with Reproduction Traits

Girish A Parmar; Jay Prakash Gupta; Jagdish D Chaudhari; Bhavesh M Prajapati; Rishit N Sathwara

Authors

Girish A Parmar Department of Animal Genetics and Breeding, Sardarkrushinagar Dantiwada Agricultural University, (SDAU)-385506, Gujarat, INDIA
Jay Prakash Gupta Department of Animal Genetics and Breeding, Sardarkrushinagar Dantiwada Agricultural University, (SDAU)-385506, Gujarat, INDIA
Jagdish D Chaudhari Department of Animal Genetics and Breeding, Sardarkrushinagar Dantiwada Agricultural University, (SDAU)-385506, Gujarat, INDIA
Bhavesh M Prajapati Department of Animal Genetics and Breeding, Sardarkrushinagar Dantiwada Agricultural University, (SDAU)-385506, Gujarat, INDIA
Rishit N Sathwara Department of Animal Genetics and Breeding, Sardarkrushinagar Dantiwada Agricultural University, (SDAU)-385506, Gujarat, INDIA

Keywords:

Single Nucleotide Polymorphism, Marker Assisted Selection, Candidate Genes, Reproduction Traits

Abstract

The genetic improvement programmes for large animals through progeny testing and pedigree selection are proven methodology for achieving a fixed genetic progress, but these are time consuming and costly. Marker Assisted Selection (MAS) is an innovative tool in animal breeding and has great potential to complement or replace the traditional breeding programme. Single Nucleotide Polymorphism (SNP) are the most common type of genetic variation in the genome. Reproductive performance is a good determinant of productivity and sustainability in farm animals. Reproduction traits determining productive life and culling decisions in dairy herds. Many SNPs have been found to be associated with reproduction traits. There are mainly two types of methods for detection of SNP genotyping: (1) traditional gel-based method and (2) high throughput method. Detection of DNA markers associated with improved reproductive performance through genome wide association studies could lead to genetic gain that is more balanced between fertility and production.