The objective of this study was to describe clinical, haemato-biochemical, radiographic, ultrasonographic and endoscopic changes in cows with traumatic reticuloperitonitis. Seventy two Jersey cross bred and thirty eight Holstein Friesian cross bred cows were diagnosed for traumatic reticuloperitonitis through ultrasonography were included in the study. On clinical examination animals had pyrexia, anorexia, arched back stance, atony of rumen and bloat. Leukocytosis with neutrophilia, significantly elevated aspartate aminotransferase and globulin values were noticed on haemato-biochemical examination. Radiography revealed presence of foreign body in the reticulum in 69.09 per cent of cases. Abnormal contour of reticulum surrounded by anechoic fluid with or without echogenic deposits were found on ultrasonographic examination. Reticuloscopy could not appreciate specific changes in reticulum. On histopathological examination reticulum showed focal hyperplasia with stray inflammatory cells. Ultrasonography was effective in diagnosing traumatic reticuloperitonitis in cows than other imaging techniques.