Anthelmintic Efficacy of Aqueous-Alcoholic Extracts Formulations of Embelia ribes Fruits and Vernonia anthelmintica Seeds against Ovine Gastrointestinal Nematodes

Abstract

Aqueous alcoholic (70% ethanol) extracts mixture of Embelia ribes fruits and Vernonia anthelmintica seeds
was evaluated for anthelmintic efficacy in sheep having natural infection of gastrointestinal nematodes.
Twelve infected sheep were randomly divided into two groups, Group I and Group II comprising six animals
each. Group I sheep were treated with Embelia ribes fruits and Vernonia anthelmintica seeds extract (1:1)
at dose rate of 100mg /kg. b.wt. orally whereas G II was kept as untreated infected control. Faecal and
blood samples from each sheep were collected on 0,3,7 and 10-day post-treatment to record egg per gram
of faeces (EPG) and haematological (Hb, PCV and TEC) and biochemical indices (Total plasma protein,
serum albumin, ALP, ALT, AST & serum creatinine). On day 10 PT, decrease in egg per gram, improvement
in haematological values and increase in serum protein level suggests promising anthelmintic values of
aqueous alcoholic extract mixture of Embelia ribes fruits and Vernonia anthelmintica seeds.