Colostrum is the early milk secreted at the time of parturition which is rich in antibodies and acts as an immune booster for post-natal calve’s health. Cow’s colostrum contains the basic alimentary constituents; fat, protein, carbohydrate, minerals and vitamins, in addition to an immunoglobulin, biological factors, hormones and other biological particles. Colostrum constituents are very crucial for immunity as calves born with weak immunity and very susceptible to infection in early age. Colostrum feeding enhances immunity of calves, so quality and quantity of colostrum should be optimized for better growth and health of calves.