Twelve crossbred (Gir Χ HF, Gir Χ Jersey) calves above 6 months of age were selected and divided randomly into two equal groups viz. Group- T1 and T2. Group- T1 (control) received standard concentrate mixture routinely used on the farm whereas Group- T2 (treatment) received concentrate mixture same as control supplemented with 3 g rumen protected methionine and 20 g rumen protected lysine/calf/day. The roughage feeding was same for both the groups. The average body weights and gain in weight of calves from treatment group were significantly (P<0.01) higher than control group. The average DM, TDN and DCP intake of calves from groups T1 and T2 were comparable, however, the average percent DM intake and DM intake per unit metabolic body size of group T1 was significantly (P<0.05) higher than treatment group T2. The efficiency of feed utilization in terms of DM, TDN intake per kg gain in weight was significantly better for treatment group T2 than control. The mean values of blood glucose, serum NEFA and BUN of calves from groups T1 and T2 showed non-significant effect of feed treatment, however, the mean serum triglycerides, VLDL, protein, albumin and globulin levels of calves from treatment group were significantly higher than control group. The digestibility of all the nutrients was significantly (P<0.05) higher for treatment group. The economics of the study revealed that the per kg weight gain cost was reduced by 2.92% in group T2 when compared with control.