Ovarian cysts are an economic problem in the goat. The primary physiological defect leading to the formation of ovarian follicular cysts in cow is a failure of the hypothalamic gonadotrophin releasing hormone (GnRH) surge to trigger the preovulatory surge of luteinizing hormone (LH) in response to oestradiol although there is no published data regarding the cause of ovrian cyst in goat.. The objective of the present study was to determine the estradiol and progesterone concentration in cystic follicular fluid of goat. The enzyme immunoassay procedure for progesterone and estradiol was performed using estradiol ELISA kit and progesterone ELISA kit respectively. Hormonal data showed higher concentration of estradiol in large follicles (1.764±0.26) as compared to cystic follicles (0.968±0.063) and Progesterone concentrations however were highest in large follicle(1.374±.0773) followed by cystic follicles (5.754±0.631).